| Rank | Title | Distributor | Weekend Gross |
Cumulative Gross |
Release Weeks |
Number of Theaters |
| 1 | Michael Jackson's This Is It | Sony | $21,300,000 | $32,500,000 | 1 | 3,481 |
| 2 | Paranormal Activity | Paramount | $16,540,000 | $84,780,000 | 6 | 2,404 |
| 3 | Law Abiding Citizen | Overture | $7,303,000 | $51,384,650 | 3 | 2,764 |
| 4 | Couples Retreat | Universal | $6,097,390 | $86,663,145 | 4 | 3,026 |
| 5 | Saw VI | Lionsgate | $5,560,000 | $22,820,000 | 2 | 3,036 |
| 6 | Where the Wild Things Are | Warner Bros. | $5,081,000 | $61,800,000 | 3 | 3,645 |
| 7 | The Stepfather | Sony | $3,400,000 | $24,748,000 | 3 | 2,346 |
| 8 | Astro Boy | Summit | $3,035,000 | $10,890,767 | 2 | 3,020 |
| 9 | Amelia | Fox Searchlight | $3,000,000 | $8,305,832 | 2 | 1,070 |
| 10 | Cirque du Freak: The Vampire's Assistant | Universal | $2,809,080 | $10,520,870 | 2 | 2,754 |
| 11 | Cloudy With a Chance of Meatballs | Sony | $2,700,000 | $118,557,000 | 7 | 2,322 |
| 12 | Zombieland | Sony | $2,600,000 | $71,161,000 | 5 | 2,056 |